2024 Early Hearing Detection & Intervention Conference

March 17-19, 2024 • Denver, CO

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3/15/2022  |   10:35 AM - 11:00 AM   |  Examining Auditory Brainstem Response Waveforms in Children with Autism Spectrum Disorder: A Retrospective Chart Review   |  Room 12

Examining Auditory Brainstem Response Waveforms in Children with Autism Spectrum Disorder: A Retrospective Chart Review

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects communication and behavior (NIMH, n.d.). Not only do individuals with ASD typically show abnormal cortex activation when processing acoustic stimuli (Claesdotter-Knutsson et al., 2019), but individuals with ASD may also have a smaller brainstem volume, due to reduced grey matter, as well as reduced superior olivary neurons (Talge et al., 2018). While behavioral signs of ASD can be observed around 18-24 months of age, children with ASD are typically not diagnosed until 3-4 years of age (Boroujeni et al. 2017; Miron et al., 2021). Therefore, the need for a timelier diagnosis is necessary, and research has speculated that this can be attained via auditory brainstem response (ABR) testing (Talge et al. 2018). ABR measurements assess the subcortical electrical activity in the auditory pathways after a sound stimulus (Claesdotter-Knutsson et al., 2019). ABRs are therefore useful for determining hearing thresholds for difficult-to-test populations. Previous research has suggested that individuals with ASD may have alterations such as lower amplitudes or delayed absolute & interpeak latencies in both click and neurodiagnostic ABRs (Rosenhall et al. 2003; Li et al., 2020). However, there is still much heterogeneity concerning the relationship between the use of ABR and the diagnosis of ASD (Talge et al. 2018). This study will perform a detailed chart review of patients seen for a neurodiagnostic ABR at Montefiore Medical Center from 2018 through September 2021.We hope our findings will foster the possibility of using the neurodiagnostic ABR as a clinical tool in the diagnosis of young children with ASD, in turn closing the gap in later age diagnosis.

  • To identify differences in auditory brainstem response waveforms in children diagnosed with autism spectrum disorder
  • To determine a relationship between auditory brainstem response and diagnosis of autism spectrum disorder
  • To examine whether auditory brainstem response testing can be used as an early marker for autism spectrum disorder

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Presenters/Authors

Elizabeth Berger (Co-Presenter,Author), Montefiore Medical Center, eliberger@montefiore.org;
Elizabeth Berger is in her final year of the Au.D. program at Montclair State University. She is currently completing her externship at Albert Einstein College of Medicine/ Montefiore Medical Center, where she is a LEND trainee.


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Ashley Andino (Primary Presenter,Author), Montefiore Medical Center, aandino@montefiore.org;
Ashley Andino in her final year of the Au.D. program at the CUNY Graduate Center. She is currently completing her externship at Albert Einstein College of Medicine/Montefiore Medical Center, where she is a LEND trainee.


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Melanie Rosenthal (Co-Presenter,Co-Author), Albert Einstein College of Medicine, mrosenth@montefiore.org;
Melanie Rosenthal, AuD is a pediatric audiologist Rose F. Kennedy Children's Evaluation and Rehabilitation Center at Montefiore Medical Center in the Bronx, NY. She is the training director for the LEND Audiology Supplemental grant and is faculty at Albert Einstein College of Medicine.


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