2025 Early Hearing Detection & Intervention Conference
March 9-11, 2025 • Pittsburgh, PA
DAVID L. LAWRENCE CONVENTION CENTER
| Investigating the relationship between Hearing loss in girls with Turner syndrome and Developmental Concerns
Investigating the relationship between Hearing loss in girls with Turner syndrome and Developmental Concerns
Turner syndrome (TS) affects ~1/2000 females and increases the risk of conductive and sensorineural hearing loss. Conductive hearing loss (CHL) prevalence in TS is 6-43%, often due to otitis media. Our hypothesis was that CHL likely correlates with speech delay in children with Turner syndrome. While known that Turner syndrome and hearing loss can both play a separate role in an individuals’ learning differences. This study investigated the relationship between CHL and speech delay in children <6 y/o with TS using the INSIGHTS registry. This study included 50 TS patients, aged 6 years old or younger with audiology data, excluding those with additional diagnoses such as autism spectrum disorder(ASD). There were 24 (48%) with abnormal hearing tests, and CHL was the most common diagnosis (70% in left ear, 75% in right ear). Of these 24 with an abnormal result, 7 patients had normal audiology exams after PE tube intervention. There were 32 patients that had speech delays. No significant association was found between abnormal audiology results and speech delay (Fisher's Exact test P-value = 0.589). Overall, our study as well as previous studies shows that there is an increase in both hearing loss and speech delay in the TS population. However, this small study highlights that there is further research that needs to be investigated in discovering the hearing loss correlation with the speech delay. While there are other co-variables that could be contributing to the increased risks for speech delay in this population, it does suggest that individuals with TS do benefit from additional audiology exams to evaluate for hearing loss and that this potentially could increase their language development. The goal is that with more research and regular audiology exams for TS individuals it will address the increased risk for hearing loss and support language development.
- To assess the relationship between conductive hearing loss and speech delay.
- To demonstrate the use of additional audiology exams in the Turner syndrome population.
- To describe the correlation between hearing loss and development in the Turner syndrome population.
Presentation:
3545975_18353OliviaIsaacks.pdf
Handouts:
Handout is not Available
Transcripts:
CART transcripts are NOT YET available, but will be posted shortly after the conference
Presenters/Authors
Olivia Isaacks
(Primary Presenter,Co-Author), olivia.isaacks@cuanschutz.edu;
Olivia Isaacks is a second year in the Masters of Genetic Counseling program at University of Colorado Anschutz Medical Campus. Olivia is a first-year trainee with LEND JFK Partners at University of Colorado Anschutz Medical Campus during August of 2024 to April 2025. She completed her bachelor’s degree in Cellular and Molecular Biology in May 2022 with three minors (Biomedical Sciences, Chemistry, Spanish) at Missouri State University. Olivia worked a couple of summers during her undergraduate degree as a paraprofessional and seven months post-undergrad as a long-term substitute teacher in Special Education. She also has many personal experiences that have led to her passion for helping individuals in this field. During her second year of graduate studies in genetic counseling and training with JFK partners, Olivia is working on two research projects related to hearing loss development. The first is investigating the relationship between hearing loss in girls with Turner syndrome and developmental concerns. The second is assessing the genetic testing yield and utility of genetic testing in individuals with unilateral hearing loss.
ASHA DISCLOSURE:
Financial -
No relevant financial relationship exists.
Nonfinancial -
No relevant nonfinancial relationship exists.
AAA DISCLOSURE:
Financial -
No relevant financial relationship exists.
Nonfinancial -
No relevant nonfinancial relationship exists.